CSTF2T

Across TCGA cell cohorts, CSTF2T RNA expression is significantly associated with the go_rna of many other GO terms, with 3,832 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CSTF2T-associated GO terms across cancer lineages are Positive regulation of mitochondrial ATP synthesis coupled electron transport, Double-strand break repair via nonhomologous end joining, and Regulation of meiosis I. Each is linked with CSTF2T in more than 16 cancer types. Because this analysis shows association rather than direction, both CSTF2T-to-partner and partner-to-CSTF2T results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial ATP synthesis coupled electron transport grouped by CSTF2T-low versus CSTF2T-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSTF2T→partner) and Y-score (partner→CSTF2T) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.126	+1.028	<.001	<.001	3	17
SKIN	Double-strand break repair via nonhomologous end joining →	+0.046	+0.670	.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of meiosis I →	+0.159	+0.902	.005	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle G2/M phase transition →	+0.080	+0.932	<.001	<.001	3	14
STOMACH	RNA 3'-end processing →	+0.080	+0.864	<.001	<.001	3	14
SOFT_TISSUE	Mitotic G2/M transition checkpoint →	+0.083	+0.896	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,832 associations by consensus.

Positive regulation of mitochondrial ATP synthesis coupled electron transport by CSTF2T expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →