CSTF2T

Across TCGA cell cohorts, CSTF2T mutation is significantly associated with the RNA expression of many other genes, with 373 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CSTF2T-associated genes across cancer lineages are WNT2, KIR2DL4, and ETDB. Each is linked with CSTF2T in more than 1 cancer types. Because this analysis shows association rather than direction, both CSTF2T-to-partner and partner-to-CSTF2T results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WNT2 grouped by CSTF2T-low versus CSTF2T-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSTF2T→partner) and Y-score (partner→CSTF2T) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	WNT2 →	+0.024	+3.977	<.001	.006	3	1
OESOPHAGUS	KIR2DL4 →	+0.122	+3.584	<.001	.008	3	1
OESOPHAGUS	ETDB →	+0.402	+3.857	.008	.002	3	1
OVARY	C18orf63 →	+0.043	+3.938	<.001	.005	3	1
LUNG_NSCLC_LUAD	WFDC6 →	+0.050	+4.887	<.001	.009	3	1
BREAST	IL17F →	+0.052	+4.736	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 373 associations by consensus.

WNT2 by CSTF2T expression — OESOPHAGUS

Explore this box plot interactively →