CSTF2

Across TCGA patient cohorts, CSTF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,767 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CSTF2-associated proteins across cancer lineages are MCM4, MCM6, and SMC4. Each is linked with CSTF2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CSTF2-to-partner and partner-to-CSTF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CSTF2 versus MCM4 in LUAD, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CSTF2→partner) and Y-score (partner→CSTF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MCM4 →	+0.840	+0.609	<.001	<.001	3	9
LUAD	MCM6 →	+0.818	+0.555	<.001	<.001	3	9
GBM	SMC4 →	+0.685	+0.414	<.001	<.001	3	8
OV	DNMT1_S714 →	+0.748	+0.552	<.001	<.001	3	8
BRCA	MCM2 →	+0.686	+0.514	<.001	<.001	3	8
BRCA	MCM3 →	+0.746	+0.537	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,767 associations by consensus.

CSTF2 vs MCM4 — LUAD

Explore this scatter interactively →