CST9L

Across TCGA patient cohorts, CST9L mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CST9L-associated genes across cancer lineages are XRCC1, P-Cadherin, and Cyclin-E2. Each is linked with CST9L in more than 1 cancer types. Because this analysis shows association rather than direction, both CST9L-to-partner and partner-to-CST9L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XRCC1 grouped by CST9L-low versus CST9L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CST9L→partner) and Y-score (partner→CST9L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	XRCC1 →	-0.191	-3.000	.020	.036	3	2
UCEC	P-Cadherin →	-0.188	-3.308	.013	.010	3	1
UCEC	Cyclin-E2 →	+0.178	+3.321	.043	.010	3	1
UCEC	Notch1 →	+0.228	+3.321	.001	.010	2	1
UCEC	Ku80 →	+0.284	+3.335	.021	.005	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

XRCC1 by CST9L expression — UCEC

Explore this box plot interactively →