CST1

Across TCGA patient cohorts, CST1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,235 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CST1-associated proteins across cancer lineages are ISLR, HMCN1, and LTBP2. Each is linked with CST1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CST1-to-partner and partner-to-CST1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CST1 versus ISLR in PDAC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CST1→partner) and Y-score (partner→CST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ISLR →	+0.635	+1.453	<.001	<.001	3	7
BRCA	HMCN1 →	+0.586	+1.963	<.001	<.001	3	5
GBM	LTBP2 →	+0.647	+0.350	<.001	.004	3	5
BRCA	PDLIM4 →	+0.540	+1.741	<.001	.001	3	5
BRCA	SGCD →	+0.629	+2.103	<.001	<.001	3	4
LSCC	TNN →	+0.702	+2.201	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,235 associations by consensus.

CST1 vs ISLR — PDAC

Explore this scatter interactively →