CST1

Across TCGA patient cohorts, CST1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,387 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CST1-associated genes across cancer lineages are CORIN, CST2, and NTM. Each is linked with CST1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CST1-to-partner and partner-to-CST1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CST1 versus CORIN in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CST1→partner) and Y-score (partner→CST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CORIN →	+0.737	+0.862	<.001	<.001	3	4
PDAC	CST2 →	+1.201	+0.819	.001	<.001	2	4
LSCC	NTM →	+0.730	+0.502	<.001	.001	3	3
UCEC	PRRX1 →	+1.134	+1.195	<.001	<.001	3	3
BRCA	FOXO1 →	+1.032	+1.028	<.001	.001	3	3
OV	FOXQ1 →	+1.442	+0.905	.001	.006	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,387 associations by consensus.

CST1 vs CORIN — UCEC

Explore this scatter interactively →