CSPG4

Across TCGA patient cohorts, CSPG4 protein abundance is significantly associated with the RNA expression of many other genes, with 13,078 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CSPG4-associated genes across cancer lineages are RFLNB, ITGA5, and CARMN. Each is linked with CSPG4 in more than 8 cancer types. Because this analysis shows association rather than direction, both CSPG4-to-partner and partner-to-CSPG4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CSPG4 versus RFLNB in BRCA, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSPG4→partner) and Y-score (partner→CSPG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RFLNB →	+0.980	+0.613	<.001	<.001	3	9
COAD	ITGA5 →	+1.047	+0.281	<.001	<.001	2	9
UCEC	CARMN →	+1.119	+0.252	<.001	.004	3	8
CCRCC	COL5A3 →	+0.949	+0.563	<.001	<.001	3	8
HNSC	INHBA →	+1.398	+0.806	<.001	<.001	3	8
CCRCC	AFAP1L1 →	+0.990	+0.563	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,078 associations by consensus.

CSPG4 vs RFLNB — BRCA

Explore this scatter interactively →