CSP2

Across TCGA pan-cancer cohorts, CSP2 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CSP2 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher CSP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CSP2 expression acts as an unfavorable survival marker, although some lineages such as SKCM and HNSC show a favorable association.

MESO, LUSC, and ACC are the cancer types where CSP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Median	All	0.251	0.469	<.001	69	view →
LUSC	OS	Median	III,IV	0.519	0.816	<.001	49	view →
ACC	OS	Tertile	All	0.370	0.779	.003	37	view →
CESC	DFS	Quartile	All	0.736	0.887	<.001	36	view →
SKCM	DFS	Quartile	II,III,IV	0.300	0.141	.002	36	view →
HNSC	DFS	Tertile	IV	0.698	0.481	.004	27	view →
READ	DFS	Median	All	0.403	0.722	.005	25	view →
LGG	OS	Median	All	0.943	0.845	<.001	25	view →
GBM	DFS	Tertile	All	0.471	0.187	.001	21	view →
LAML	DFS	Median	All	0.431	0.713	.003	20	view →
UVM	OS	Median	All	0.874	0.598	.001	18	view →
UCEC	DFS	Quartile	III,IV	0.415	0.716	.023	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CSP2–MESO (DFS)

Open the MESO breakdown →