Q-omics provides the consensus-scored CSP2 profile across patient tissues and cancer cell-line models. CSP2 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, CSP2 is differentially expressed in 13, with the highest sampling consensus in LUAD. Additionally, CSP2 RNA expression shows 17,076 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight MESO, LUAD, and THYM as cancer lineages where CSP2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CSP2 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CSP2 survival associations across molecular data types. CSP2 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CSP2 RNA expression–survival associations across cancer types. High CSP2 expression shows unfavorable associations in MESO, LUSC, ACC and CESC, but favorable associations in SKCM and HNSC. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for CSP2 RNA expression.
This table summarizes CSP2 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in LUAD for RNA.
This table ranks reproducible tumor–normal expression differences for CSP2. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CSP2 shows lower tumor expression in LUAD, UCEC, BLCA, THCA, KICH and BRCA. The LUAD box plot shows higher CSP2 RNA expression in normal versus tumor tissue (log2 FC = −0.527, t-test p < 0.001).
This table shows molecular features associated with CSP2 in patient tissues and cancer cell lines. In patient samples, CSP2 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
