CSNK2A3

Across TCGA cell cohorts, CSNK2A3 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CSNK2A3-associated genes across cancer lineages are XAGE5, IQCF2, and GPR171. Each is linked with CSNK2A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSNK2A3-to-partner and partner-to-CSNK2A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XAGE5 grouped by CSNK2A3-low versus CSNK2A3-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK2A3→partner) and Y-score (partner→CSNK2A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	XAGE5 →	+0.255	+5.196	<.001	.005	3	1
OVARY	IQCF2 →	+0.052	+5.196	<.001	.005	3	1
LARGE_INTESTINE	GPR171 →	+0.019	+4.273	<.001	.006	3	1
LARGE_INTESTINE	CCL18 →	+0.097	+4.415	<.001	.007	3	1
CNS	MBD3L1 →	+0.039	+5.754	<.001	.002	3	1
LUNG_NSCLC_LUAD	HSF5 →	+0.009	+3.977	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

XAGE5 by CSNK2A3 expression — OVARY

Explore this box plot interactively →