CSNK2A3

Across TCGA pan-cancer cohorts, CSNK2A3 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated CSNK2A3 data layer compared with 7 for mutation status.

The strongest signal is observed in mesothelioma (MESO), where higher CSNK2A3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CSNK2A3 expression acts as an unfavorable survival marker, although some lineages such as KIRC and READ show a favorable association.

MESO, LIHC, and KIRC are the cancer types where CSNK2A3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.410	0.656	<.001	107	view →
LIHC	DFS	Median	All	0.462	0.612	<.001	71	view →
KIRC	DFS	Tertile	II,III,IV	0.857	0.530	<.001	60	view →
UVM	OS	Quartile	III,IV	0.442	0.933	<.001	35	view →
READ	DFS	Quartile	All	0.966	0.762	.002	34	view →
BLCA	DFS	Median	II,III,IV	0.562	0.663	.004	29	view →
SARC	OS	Quartile	All	0.291	0.694	<.001	26	view →
KIRP	OS	Tertile	All	0.870	0.948	.010	24	view →
UCEC	DFS	Tertile	All	0.793	0.897	.002	24	view →
THCA	OS	Median	III,IV	0.859	0.969	.024	16	view →
PRAD	DFS	Quartile	All	0.965	0.904	.005	14	view →
PAAD	DFS	Tertile	All	0.166	0.338	.034	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

CSNK2A3–MESO (OS)

Open the MESO breakdown →