CSNK2A2

Across TCGA patient cohorts, CSNK2A2 mutation is significantly associated with the RNA expression of many other genes, with 2,456 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSNK2A2-associated genes across cancer lineages are RPS17P15, LINC01943, and ARRDC3-AS1. Each is linked with CSNK2A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSNK2A2-to-partner and partner-to-CSNK2A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS17P15 grouped by CSNK2A2-low versus CSNK2A2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK2A2→partner) and Y-score (partner→CSNK2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPS17P15 →	+0.202	+4.197	<.001	.009	3	2
UCEC	LINC01943 →	+0.461	+1.797	.001	.008	3	1
UCEC	ARRDC3-AS1 →	+0.260	+2.191	.001	.002	3	1
BRCA	RNU4-67P →	+0.511	+7.731	<.001	.009	3	1
BRCA	RN7SKP221 →	+0.099	+8.471	<.001	.005	3	1
BRCA	TRDD1 →	+1.367	+9.057	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,456 associations by consensus.

RPS17P15 by CSNK2A2 expression — HNSC

Explore this box plot interactively →