CSNK2A2

Across TCGA pan-cancer cohorts, CSNK2A2 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of CSNK2A2’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CSNK2A2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CSNK2A2 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

HNSC, COAD, and KIRC are the cancer types where CSNK2A2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CSNK2A2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+1.047	<.001	12	view →
COAD	Female	II,III,IV	+1.031	<.001	12	view →
KIRC	Female	All	+0.746	<.001	12	view →
KIRP	All	II,III,IV	+1.173	<.001	11	view →
LIHC	Female	II,III,IV	+0.795	<.001	9	view →
BLCA	All	All	+0.486	.001	9	view →
LUSC	All	II,III,IV	+0.478	<.001	6	view →
BRCA	Female	All	−0.279	<.001	6	view →
CHOL	Male	All	+1.616	<.001	5	view →
STAD	Male	II,III,IV	+0.864	.002	5	view →
THCA	Male	All	+0.229	.016	4	view →
READ	All	III,IV	+0.834	.028	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

CSNK2A2–HNSC

Open the HNSC breakdown →