CSNK2A2

Across TCGA patient cohorts, CSNK2A2 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSNK2A2-associated genes across cancer lineages are Notch1, EGFR_pY1068, and eIF4E. Each is linked with CSNK2A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSNK2A2-to-partner and partner-to-CSNK2A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by CSNK2A2-low versus CSNK2A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK2A2→partner) and Y-score (partner→CSNK2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.173	+2.009	.002	.017	3	2
UCEC	EGFR_pY1068 →	-0.210	-1.906	.038	.016	3	1
UCEC	eIF4E →	+0.171	+2.820	.044	.035	3	1
UCEC	ERK2 →	+0.234	+1.906	.002	.016	3	1
UCEC	JNK_pT183_Y185 →	-0.193	-1.893	.004	.016	3	1
UCEC	Lck →	+0.178	+1.906	.027	.016	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Notch1 by CSNK2A2 expression — UCEC

Explore this box plot interactively →