CSNK1G1

Across TCGA patient cohorts, CSNK1G1 mutation is significantly associated with the RNA expression of many other genes, with 4,820 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSNK1G1-associated genes across cancer lineages are RNU6-1274P, MIR4774, and CYCSP53. Each is linked with CSNK1G1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSNK1G1-to-partner and partner-to-CSNK1G1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1274P grouped by CSNK1G1-low versus CSNK1G1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK1G1→partner) and Y-score (partner→CSNK1G1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RNU6-1274P →	+0.403	+4.925	<.001	.004	3	2
READ	MIR4774 →	+0.627	+5.257	<.001	.002	3	2
PRAD	CYCSP53 →	+0.184	+7.939	<.001	.008	3	2
UCEC	MIR6780B →	+0.198	+1.790	<.001	.005	3	2
UCEC	MIR3193 →	+0.394	+1.597	<.001	.002	3	2
SKCM	IGHD6-19 →	+2.037	+3.313	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,820 associations by consensus.

RNU6-1274P by CSNK1G1 expression — READ

Explore this box plot interactively →