CSN3

Across TCGA patient cohorts, CSN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,657 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CSN3-associated GO terms across cancer lineages are T cell receptor signaling pathway, Myeloid leukocyte differentiation, and Positive regulation of interleukin-4 production. Each is linked with CSN3 in more than 10 cancer types. Because this analysis shows association rather than direction, both CSN3-to-partner and partner-to-CSN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T cell receptor signaling pathway grouped by CSN3-low versus CSN3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSN3→partner) and Y-score (partner→CSN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	T cell receptor signaling pathway →	+0.069	+0.155	<.001	<.001	3	11
STAD	Myeloid leukocyte differentiation →	+0.065	+0.206	<.001	<.001	3	10
THCA	Positive regulation of interleukin-4 production →	+0.077	+0.016	<.001	<.001	3	10
STAD	Alpha-beta T cell activation →	+0.063	+0.136	<.001	<.001	3	10
STAD	Antigen receptor-mediated signaling pathway →	+0.079	+0.144	<.001	<.001	3	10
STAD	Regulation of B cell activation →	+0.068	+0.135	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,657 associations by consensus.

T cell receptor signaling pathway by CSN3 expression — STAD

Explore this box plot interactively →