CSN3

Across TCGA patient cohorts, CSN3 protein abundance is significantly associated with the protein abundance of many other proteins, with 772 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CSN3-associated proteins across cancer lineages are ARHGEF11_S592, ADGRE5_T817, and CCDC6_S327. Each is linked with CSN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSN3-to-partner and partner-to-CSN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CSN3 versus ARHGEF11_S592 in BRCA, with a Pearson correlation of -0.34.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CSN3→partner) and Y-score (partner→CSN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARHGEF11_S592 →	-0.746	-0.784	<.001	<.001	3	1
BRCA	ADGRE5_T817 →	+0.577	+1.334	<.001	<.001	3	1
BRCA	CCDC6_S327 →	-1.434	-2.122	<.001	<.001	3	1
BRCA	CCNH →	-0.215	-0.648	<.001	<.001	3	1
BRCA	CDK19_S449 →	+0.592	+1.332	<.001	<.001	3	1
BRCA	CEP170_S379 →	+1.121	+0.992	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 772 associations by consensus.

CSN3 vs ARHGEF11_S592 — BRCA

Explore this scatter interactively →