CSN1S1

Across TCGA patient cohorts, CSN1S1 protein abundance is significantly associated with the RNA expression of many other genes, with 520 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CSN1S1-associated genes across cancer lineages are PARK7P2, PORCN, and KIR3DX1. Each is linked with CSN1S1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSN1S1-to-partner and partner-to-CSN1S1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CSN1S1 versus PARK7P2 in BRCA, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSN1S1→partner) and Y-score (partner→CSN1S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PARK7P2 →	+0.388	+1.673	.002	.005	3	1
LSCC	PORCN →	+0.665	+2.276	.004	.003	3	1
LSCC	KIR3DX1 →	+0.084	+2.219	.007	.009	3	1
LSCC	GRIN2D →	+0.709	+2.355	.004	.002	3	1
LSCC	MEGF9 →	-1.477	-2.690	.002	.008	3	1
LSCC	CPE →	+1.520	+2.222	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 520 associations by consensus.

CSN1S1 vs PARK7P2 — BRCA

Explore this scatter interactively →