CSN1S1

Across TCGA cell cohorts, CSN1S1 RNA expression is significantly associated with the go_rna of many other GO terms, with 116 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CSN1S1-associated GO terms across cancer lineages are Response to amine, Citrulline biosynthetic process, and Positive regulation of neurotrophin TRK receptor signaling pathway. Each is linked with CSN1S1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CSN1S1-to-partner and partner-to-CSN1S1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to amine grouped by CSN1S1-low versus CSN1S1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSN1S1→partner) and Y-score (partner→CSN1S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Response to amine →	+0.126	+0.557	<.001	.003	3	2
SOFT_TISSUE	Citrulline biosynthetic process →	+0.134	+0.552	.002	.003	3	2
SOFT_TISSUE	Positive regulation of neurotrophin TRK receptor signaling pathway →	+0.210	+0.703	<.001	.007	3	2
SOFT_TISSUE	CAMKK-AMPK signaling cascade →	+0.083	+0.553	.007	.003	3	2
SOFT_TISSUE	L-methionine biosynthetic process →	+0.061	+0.532	.009	.005	3	2
SOFT_TISSUE	Purine nucleoside diphosphate metabolic process →	-0.048	-0.763	.008	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 116 associations by consensus.

Response to amine by CSN1S1 expression — SOFT_TISSUE

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