CSMD2

Across TCGA patient cohorts, CSMD2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,456 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CSMD2-associated genes across cancer lineages are SNRPD3, EIF3L, and SNU13. Each is linked with CSMD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSMD2-to-partner and partner-to-CSMD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CSMD2 versus SNRPD3 in GBM, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSMD2→partner) and Y-score (partner→CSMD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.528	+0.412	<.001	<.001	3	1
GBM	EIF3L →	+0.324	+0.255	<.001	.007	3	1
GBM	SNU13 →	+0.336	+0.304	<.001	.001	3	1
GBM	POLR2F →	+0.516	+0.354	<.001	<.001	3	1
GBM	SOX10 →	+1.519	+0.268	<.001	.004	3	1
GBM	SEPTIN3 →	+1.112	+0.348	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,456 associations by consensus.

CSMD2 vs SNRPD3 — GBM

Explore this scatter interactively →