CSMD2

Across TCGA cell cohorts, CSMD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,777 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CSMD2-associated GO terms across cancer lineages are Protein localization to vacuole, Regulation of intrinsic apoptotic signaling pathway, and Regulation of spindle assembly. Each is linked with CSMD2 in more than 6 cancer types. Because this analysis shows association rather than direction, both CSMD2-to-partner and partner-to-CSMD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to vacuole grouped by CSMD2-low versus CSMD2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSMD2→partner) and Y-score (partner→CSMD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein localization to vacuole →	+0.053	+1.872	.006	<.001	3	7
SOFT_TISSUE	Regulation of intrinsic apoptotic signaling pathway →	+0.092	+1.267	<.001	.002	3	7
OVARY	Regulation of spindle assembly →	+0.070	+0.094	.001	.006	3	6
SKIN	Glial cell-neuron signaling →	-0.087	-0.450	.001	.003	2	7
CNS	Positive regulation of blood pressure by epinephrine-norepinephrine →	+0.108	+1.329	.001	.003	3	6
SKIN	Protein insertion into ER membrane →	+0.116	+0.769	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,777 associations by consensus.

Protein localization to vacuole by CSMD2 expression — LUNG_SCLC

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