CSF3R

Across TCGA cell cohorts, CSF3R RNA expression is significantly associated with the go_rna of many other GO terms, with 2,559 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CSF3R-associated GO terms across cancer lineages are Maintenance of unfolded protein, Glycerolipid biosynthetic process, and Positive regulation of plasma cell differentiation. Each is linked with CSF3R in more than 7 cancer types. Because this analysis shows association rather than direction, both CSF3R-to-partner and partner-to-CSF3R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of unfolded protein grouped by CSF3R-low versus CSF3R-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSF3R→partner) and Y-score (partner→CSF3R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Maintenance of unfolded protein →	+0.108	+0.407	<.001	.008	3	8
BLOOD_Leukemia	Glycerolipid biosynthetic process →	+0.019	+2.444	.006	.002	3	6
BREAST	Positive regulation of plasma cell differentiation →	+0.130	+0.900	<.001	.009	3	5
BREAST	Intracellular pH reduction →	+0.073	+0.906	<.001	<.001	3	5
BLOOD_Leukemia	Sterol transport →	+0.054	+2.604	<.001	<.001	3	5
BLOOD_Leukemia	Positive regulation of protein localization to endoplasmic reticulum →	+0.068	+2.448	.003	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,559 associations by consensus.

Maintenance of unfolded protein by CSF3R expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →