CSAD

Across TCGA cell cohorts, CSAD RNA expression is significantly associated with the go_rna of many other GO terms, with 4,935 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CSAD-associated GO terms across cancer lineages are L-cysteine catabolic process, Taurine biosynthetic process, and Alkanesulfonate biosynthetic process. Each is linked with CSAD in more than 18 cancer types. Because this analysis shows association rather than direction, both CSAD-to-partner and partner-to-CSAD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-cysteine catabolic process grouped by CSAD-low versus CSAD-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSAD→partner) and Y-score (partner→CSAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	L-cysteine catabolic process →	+0.837	+1.161	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Taurine biosynthetic process →	+0.963	+1.668	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Alkanesulfonate biosynthetic process →	+0.963	+1.668	<.001	<.001	3	18
OESOPHAGUS	mRNA splice site recognition →	+0.149	+1.258	<.001	<.001	3	17
URINARY_TRACT	Sperm motility →	-0.144	-1.968	<.001	<.001	3	15
OESOPHAGUS	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.160	+1.992	.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,935 associations by consensus.

L-cysteine catabolic process by CSAD expression — LARGE_INTESTINE

Explore this box plot interactively →