CSAD

Across TCGA pan-cancer cohorts, CSAD RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of CSAD’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CSAD RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CSAD is over-expressed in tumor, although a few such as LIHC and BRCA show the opposite, repressed pattern.

KIRC, COAD, and LIHC are the cancer types where CSAD tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CSAD RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.439	<.001	10	view →
COAD	Female	All	+0.738	<.001	8	view →
LIHC	Female	All	−0.928	<.001	7	view →
BRCA	Female	All	−0.723	<.001	6	view →
READ	All	All	+0.828	.005	2	view →
CHOL	Female	All	−0.536	.004	2	view →
KICH	All	All	−0.376	.028	1	view →
THCA	All	All	+0.247	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

CSAD–KIRC

Open the KIRC breakdown →