CRYZP1

Across TCGA pan-cancer cohorts, CRYZP1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CRYZP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CRYZP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CRYZP1 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

HNSC, THCA, and CHOL are the cancer types where CRYZP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CRYZP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.171	<.001	7	view →
THCA	All	All	−0.288	<.001	5	view →
CHOL	All	All	+0.597	.001	4	view →
LIHC	All	All	+0.068	.001	4	view →
KIRC	All	All	+0.129	.007	3	view →
READ	All	III,IV	+0.509	.027	2	view →
BRCA	All	III,IV	−0.276	.043	2	view →
COAD	Male	All	+0.274	.015	2	view →
PRAD	All	All	+0.226	.035	2	view →
KIRP	All	IV	+0.177	.017	2	view →
KICH	Female	All	−0.182	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CRYZP1–HNSC

Open the HNSC breakdown →