CRYZL2P

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CRYZL2P Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CRYZL2P data layer compared with 23 for mass-spec protein.

The strongest signal is observed in sarcoma (SARC), where higher CRYZL2P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CRYZL2P expression acts as an unfavorable survival marker.

SARC and UCEC are the cancer types where CRYZL2P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SARCOSMedianAll0.1750.745.0076view →
UCECOSMedianIV0.2310.592.0366view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CRYZL2P–SARC (OS)

Kaplan–Meier survival curve for CRYZL2P mutant vs wild-type samples in SARC.

Open the SARC breakdown →

Exploration