Across TCGA patient cohorts, CRYZL1 mutation is significantly associated with the RNA expression of many other genes, with 879 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CRYZL1-associated genes across cancer lineages are RNU6-517P, BLOC1S2P1, and OR2E1P. Each is linked with CRYZL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRYZL1-to-partner and partner-to-CRYZL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYZL1→partner) and Y-score (partner→CRYZL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-517P →	+0.341	+5.201	<.001	.007	3	2
BLCA	BLOC1S2P1 →	+0.158	+5.588	<.001	.004	3	2
UCEC	OR2E1P →	+0.075	+3.153	.006	.006	3	2
UCEC	UBTFL7 →	+0.105	+2.813	.002	<.001	3	2
UCEC	H3P18 →	+0.562	+2.296	<.001	.003	3	2
UCEC	TRIM53CP →	+0.438	+2.050	.002	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 879 associations by consensus.

Exploration

CRYZL1 survival (RNA) · tumor vs normal (RNA) · all CRYZL1 data types