CRYZ

Across TCGA patient cohorts, CRYZ protein abundance is significantly associated with the RNA expression of many other genes, with 13,049 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CRYZ-associated genes across cancer lineages are AURKA, TPX2, and CDKN3. Each is linked with CRYZ in more than 6 cancer types. Because this analysis shows association rather than direction, both CRYZ-to-partner and partner-to-CRYZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYZ versus AURKA in BRCA, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYZ→partner) and Y-score (partner→CRYZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AURKA →	-1.229	-0.542	<.001	<.001	3	7
BRCA	TPX2 →	-1.325	-0.463	<.001	<.001	3	7
OV	CDKN3 →	-0.960	-0.451	.003	.009	3	7
BRCA	CCNB2 →	-1.298	-0.536	<.001	<.001	3	7
BRCA	PRR11 →	-1.062	-0.415	<.001	<.001	3	7
BRCA	NDC80 →	-1.027	-0.484	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,049 associations by consensus.

CRYZ vs AURKA — BRCA

Explore this scatter interactively →