CRYZ

Across TCGA patient cohorts, CRYZ protein abundance is significantly associated with the protein abundance of many other proteins, with 23,461 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CRYZ-associated proteins across cancer lineages are NCAPG, BCKDHB, and CRYL1. Each is linked with CRYZ in more than 8 cancer types. Because this analysis shows association rather than direction, both CRYZ-to-partner and partner-to-CRYZ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYZ versus NCAPG in PDAC, with a Pearson correlation of -0.39.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYZ→partner) and Y-score (partner→CRYZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	NCAPG →	-0.614	-0.407	<.001	<.001	3	9
UCEC	BCKDHB →	+0.502	+0.520	.002	.001	3	9
UCEC	CRYL1 →	+0.519	+0.484	<.001	<.001	3	9
LSCC	SMC2 →	-0.595	-0.397	<.001	<.001	3	8
BRCA	HYI →	+0.600	+0.480	<.001	<.001	3	8
BRCA	MCEE →	+0.476	+0.465	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,461 associations by consensus.

CRYZ vs NCAPG — PDAC

Explore this scatter interactively →