CRYZ

Across TCGA cell cohorts, CRYZ RNA expression is significantly associated with the go_rna of many other GO terms, with 2,467 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CRYZ-associated GO terms across cancer lineages are Response to rapamycin, Positive regulation of centriole replication, and Positive regulation of cation transmembrane transport. Each is linked with CRYZ in more than 9 cancer types. Because this analysis shows association rather than direction, both CRYZ-to-partner and partner-to-CRYZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to rapamycin grouped by CRYZ-low versus CRYZ-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYZ→partner) and Y-score (partner→CRYZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Response to rapamycin →	-0.115	-0.945	.003	.005	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of centriole replication →	+0.090	+1.086	<.001	<.001	3	8
BLOOD_Myeloma	Positive regulation of cation transmembrane transport →	-0.077	-1.257	<.001	.002	3	7
BLOOD_Leukemia	Cellular response to ether →	-0.104	-0.879	.003	.001	3	7
SKIN	Meiotic sister chromatid cohesion →	+0.099	+0.636	<.001	.002	3	6
OVARY	Regulation of kidney size →	+1.223	+0.693	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,467 associations by consensus.

Response to rapamycin by CRYZ expression — LIVER

Explore this box plot interactively →