Across TCGA patient cohorts, CRYGS RNA expression is significantly associated with the protein abundance of many other proteins, with 10,090 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CRYGS-associated proteins across cancer lineages are SASH1_S923, UBA2, and FNDC3A_S203. Each is linked with CRYGS in more than 4 cancer types. Because this analysis shows association rather than direction, both CRYGS-to-partner and partner-to-CRYGS results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYGS→partner) and Y-score (partner→CRYGS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SASH1_S923 →	-0.368	-0.458	.001	.001	3	4
COAD	UBA2 →	+0.271	+0.471	.001	.001	2	5
PDAC	FNDC3A_S203 →	-0.389	-0.499	<.001	<.001	3	4
PDAC	AP2B1 →	+0.310	+0.447	.001	<.001	3	4
GBM	ZNF148 →	+0.366	+0.535	<.001	.001	3	3
HNSC	TBL1XR1 →	+0.424	+0.799	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,090 associations by consensus.

Exploration

CRYGS survival (RNA) · tumor vs normal (RNA) · all CRYGS data types