CRYGD

Across TCGA patient cohorts, CRYGD protein abundance is significantly associated with the RNA expression of many other genes, with 627 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CRYGD-associated genes across cancer lineages are GCAT, DDX17, and NEFH. Each is linked with CRYGD in more than 1 cancer types. Because this analysis shows association rather than direction, both CRYGD-to-partner and partner-to-CRYGD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYGD versus GCAT in PDAC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYGD→partner) and Y-score (partner→CRYGD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	GCAT →	+0.681	+0.587	.002	<.001	3	1
PDAC	DDX17 →	-0.378	-0.629	.003	.004	3	1
PDAC	NEFH →	-0.328	-0.761	.001	<.001	3	1
PDAC	TNRC6B →	-0.425	-0.742	.001	.001	3	1
PDAC	EP300 →	-0.470	-0.496	.001	.006	3	1
PDAC	CHADL →	-0.516	-0.514	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 627 associations by consensus.

CRYGD vs GCAT — PDAC

Explore this scatter interactively →