CRYBB3

Across TCGA cell cohorts, CRYBB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,560 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CRYBB3-associated GO terms across cancer lineages are Protein-RNA complex organization, GDP-L-fucose biosynthetic process, and Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Each is linked with CRYBB3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CRYBB3-to-partner and partner-to-CRYBB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-RNA complex organization grouped by CRYBB3-low versus CRYBB3-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBB3→partner) and Y-score (partner→CRYBB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Protein-RNA complex organization →	+0.054	+0.052	.002	.004	3	6
LUNG_SCLC	GDP-L-fucose biosynthetic process →	+0.126	+0.230	<.001	.001	3	6
SOFT_TISSUE	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.066	+0.110	<.001	.005	3	5
SKIN	G protein-coupled purinergic nucleotide receptor signaling pathway →	+0.896	+0.112	<.001	.003	3	5
LUNG_SCLC	Negative regulation of type I interferon-mediated signaling pathway →	+0.107	+0.194	<.001	.001	3	5
CNS	Telomerase RNA localization to Cajal body →	+0.050	+0.104	.003	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,560 associations by consensus.

Protein-RNA complex organization by CRYBB3 expression — BLOOD_Myeloma

Explore this box plot interactively →