CRYBB2P1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CRYBB2P1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CRYBB2P1 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CRYBB2P1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CRYBB2P1 expression acts as an unfavorable survival marker.

PDAC and GBM are the cancer types where CRYBB2P1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACOSQuartileAll0.5870.992.0327view →
GBMOSTertileAll0.7760.918.0016view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CRYBB2P1–PDAC (OS)

Kaplan–Meier survival curve for CRYBB2P1 mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration