CRYBB2P1

Across TCGA patient cohorts, CRYBB2P1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,396 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRYBB2P1-associated genes across cancer lineages are TMEM106A, CSF3R, and MIR223HG. Each is linked with CRYBB2P1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CRYBB2P1-to-partner and partner-to-CRYBB2P1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYBB2P1 versus TMEM106A in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBB2P1→partner) and Y-score (partner→CRYBB2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TMEM106A →	+0.863	+0.890	.002	.001	3	4
HNSC	CSF3R →	+1.385	+0.980	.001	<.001	3	4
GBM	MIR223HG →	+1.185	+0.869	<.001	<.001	3	4
HNSC	CASS4 →	+0.950	+0.865	<.001	.002	3	4
UCEC	NLRC4 →	+0.985	+0.826	.009	.002	3	4
GBM	LY86 →	+0.837	+0.595	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,396 associations by consensus.

CRYBB2P1 vs TMEM106A — BRCA

Explore this scatter interactively →