CRYBB1

Across TCGA patient cohorts, CRYBB1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,959 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRYBB1-associated genes across cancer lineages are FOLR2, LY86, and ARHGAP9. Each is linked with CRYBB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CRYBB1-to-partner and partner-to-CRYBB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYBB1 versus FOLR2 in GBM, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBB1→partner) and Y-score (partner→CRYBB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FOLR2 →	+1.256	+0.755	<.001	<.001	3	5
GBM	LY86 →	+0.951	+0.726	<.001	<.001	3	4
GBM	ARHGAP9 →	+0.636	+0.642	<.001	<.001	3	4
GBM	FAM78A →	+0.607	+0.604	<.001	<.001	3	4
LSCC	WDFY4 →	+0.822	+0.402	.001	.001	3	4
GBM	SLCO2B1 →	+0.942	+0.654	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,959 associations by consensus.

CRYBB1 vs FOLR2 — GBM

Explore this scatter interactively →