CRYBA4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CRYBA4 mutation is significantly associated with the RNA expression of many other genes, with 714 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CRYBA4-associated genes across cancer lineages are MIR4435-1, NCAPH2, and RNU6-267P. Each is linked with CRYBA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRYBA4-to-partner and partner-to-CRYBA4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBA4→partner) and Y-score (partner→CRYBA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMIR4435-1 →+0.165+2.715.002.00532
SKCMNCAPH2 →+0.519+3.208.003.00932
LUSCRNU6-267P →+0.488+3.750<.001.00132
LUSCATP5MGP6 →+0.359+4.621<.001<.00132
UCECRNU6-668P →+0.205+2.771<.001.00332
SKCMRNU6-433P →+0.164+3.758<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 714 associations by consensus.

Exploration