Across TCGA cell cohorts, CRYBA4 mutation is significantly associated with the mutation status of many other genes, with 38 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CRYBA4-associated genes across cancer lineages are SLC39A10, COL13A1, and KLHL14. Each is linked with CRYBA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRYBA4-to-partner and partner-to-CRYBA4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBA4→partner) and Y-score (partner→CRYBA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SLC39A10 →	+5.824	+5.824	.002	.002	1	1
SKIN	COL13A1 →	+4.824	+5.392	.004	.004	1	1
SKIN	KLHL14 →	+4.239	+5.053	.007	.007	1	1
SKIN	GPRC5A →	+4.239	+5.053	.007	.007	1	1
SKIN	SP110 →	+4.824	+5.392	.004	.004	1	1
SKIN	GCC2 →	+4.239	+5.053	.007	.007	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

CRYBA4 survival (RNA) · tumor vs normal (RNA) · all CRYBA4 data types