CRYBA2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CRYBA2 protein abundance is significantly associated with the RNA expression of many other genes, with 775 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CRYBA2-associated genes across cancer lineages are LGALS1, NFATC4, and DOK5. Each is linked with CRYBA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRYBA2-to-partner and partner-to-CRYBA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYBA2 versus LGALS1 in COAD, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBA2→partner) and Y-score (partner→CRYBA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADLGALS1 →+0.814+1.053.006.00531
COADNFATC4 →+0.528+1.058.001<.00131
COADDOK5 →+0.591+1.283.002<.00131
COADSYNDIG1 →+0.670+1.160.001<.00131
COADCHRDL1 →+1.269+0.837.001.00431
COADSRPX →+1.290+1.376<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 775 associations by consensus.

CRYBA2 vs LGALS1 — COAD

Per-sample scatter of CRYBA2 vs LGALS1 in COAD (Pearson r = 0.43).

Explore this scatter interactively →

Exploration