CRYBA2

Across TCGA cell cohorts, CRYBA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,474 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CRYBA2-associated GO terms across cancer lineages are Establishment of protein localization to endoplasmic reticulum, Regulation of myoblast fusion, and Regulation of protein localization to mitochondrion. Each is linked with CRYBA2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CRYBA2-to-partner and partner-to-CRYBA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to endoplasmic reticulum grouped by CRYBA2-low versus CRYBA2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYBA2→partner) and Y-score (partner→CRYBA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Establishment of protein localization to endoplasmic reticulum →	+0.085	+2.453	<.001	<.001	3	5
LUNG_SCLC	Regulation of myoblast fusion →	+0.080	+1.759	<.001	<.001	3	5
LUNG_SCLC	Regulation of protein localization to mitochondrion →	+0.073	+1.571	.001	.007	3	5
LUNG_SCLC	Pallium development →	+0.069	+1.839	.001	.002	3	5
LUNG_SCLC	Regulation of chromosome organization →	+0.050	+1.562	<.001	<.001	3	5
LUNG_SCLC	Negative regulation of RNA splicing →	+0.058	+1.292	.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,474 associations by consensus.

Establishment of protein localization to endoplasmic reticulum by CRYBA2 expression — LUNG_SCLC

Explore this box plot interactively →