CRYAB

Across TCGA pan-cancer cohorts, CRYAB Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated CRYAB data layer compared with 28 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CRYAB Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CRYAB expression acts as an unfavorable survival marker.

KIRC are the cancer types where CRYAB Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.151	0.628	.045	6	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

CRYAB–KIRC (OS)

Open the KIRC breakdown →