CRYAB

Across TCGA patient cohorts, CRYAB protein abundance is significantly associated with the RNA expression of many other genes, with 12,751 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRYAB-associated genes across cancer lineages are ASPA, SGCA, and DIPK2B. Each is linked with CRYAB in more than 6 cancer types. Because this analysis shows association rather than direction, both CRYAB-to-partner and partner-to-CRYAB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRYAB versus ASPA in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYAB→partner) and Y-score (partner→CRYAB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ASPA →	+0.645	+0.749	.001	.006	3	7
HNSC	SGCA →	+1.284	+0.994	<.001	<.001	3	7
UCEC	DIPK2B →	+0.726	+0.615	<.001	.002	3	7
OV	PTH1R →	+0.625	+0.839	.002	.003	3	7
UCEC	TAL1 →	+0.461	+0.488	.001	.006	3	7
UCEC	LMOD1 →	+1.577	+0.553	<.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,751 associations by consensus.

CRYAB vs ASPA — BRCA

Explore this scatter interactively →