CRY2

Across TCGA patient cohorts, CRY2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,522 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRY2-associated genes across cancer lineages are KAT2B, PREPL, and LCA5L. Each is linked with CRY2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CRY2-to-partner and partner-to-CRY2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRY2 versus KAT2B in BRCA, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRY2→partner) and Y-score (partner→CRY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KAT2B →	+0.797	+0.348	.001	.001	3	3
BRCA	PREPL →	+0.873	+0.373	.002	.001	3	2
BRCA	LCA5L →	+0.666	+0.287	.002	.003	3	2
UCEC	AQP3 →	-1.108	-0.224	.003	.008	3	2
UCEC	CFL2 →	+0.602	+0.314	.001	<.001	3	2
PDAC	TRDV1 →	+1.001	+0.363	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,522 associations by consensus.

CRY2 vs KAT2B — BRCA

Explore this scatter interactively →