CRY1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CRY1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,827 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CRY1-associated genes across cancer lineages are CLCA4, RDH10, and LRATD1. Each is linked with CRY1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRY1-to-partner and partner-to-CRY1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRY1 versus CLCA4 in UCEC, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRY1→partner) and Y-score (partner→CRY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCLCA4 →+2.252+0.434.002.00132
LUADRDH10 →+1.578+0.441<.001.00132
LUADLRATD1 →+1.527+0.602.006.00332
UCECTSPAN4 →-1.320-0.434.001.00132
UCECRNU1-58P →+4.529+0.589<.001.00232
UCECMIR4772 →-1.808-0.411.008.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,827 associations by consensus.

CRY1 vs CLCA4 — UCEC

Per-sample scatter of CRY1 vs CLCA4 in UCEC (Pearson r = 0.66).

Explore this scatter interactively →

Exploration