CRTC3-AS1

Across TCGA pan-cancer cohorts, CRTC3-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated CRTC3-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher CRTC3-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CRTC3-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

UCS, KICH, and LIHC are the cancer types where CRTC3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	II,III,IV	0.695	0.286	<.001	112	view →
KICH	DFS	Quartile	II,III,IV	0.434	1.000	.001	77	view →
LIHC	DFS	Quartile	All	0.314	0.527	<.001	46	view →
ACC	DFS	Median	All	0.294	0.748	.002	32	view →
BRCA	DFS	Tertile	III,IV	0.918	0.803	.004	27	view →
OV	DFS	Tertile	III,IV	0.588	0.448	.004	26	view →
STAD	OS	Median	IV	0.564	0.192	.004	18	view →
LUAD	DFS	Median	III,IV	0.785	0.532	.012	17	view →
CHOL	OS	Median	III,IV	0.286	1.000	.008	15	view →
KIRP	DFS	Median	All	0.977	0.792	.007	14	view →
MESO	OS	Tertile	All	0.752	0.379	.012	12	view →
READ	DFS	Quartile	II,III,IV	0.851	0.222	.012	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

CRTC3-AS1–UCS (OS)

Open the UCS breakdown →