CRTC3-AS1

Across TCGA pan-cancer cohorts, CRTC3-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of CRTC3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CRTC3-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CRTC3-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and BLCA are the cancer types where CRTC3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CRTC3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−0.801	<.001	9	view →
THCA	Male	III,IV	−0.718	<.001	9	view →
BLCA	All	All	+0.602	<.001	9	view →
LIHC	Male	All	+0.356	<.001	9	view →
UCEC	All	III,IV	+0.715	.003	6	view →
LUAD	Male	All	+0.698	<.001	6	view →
BRCA	All	II,III,IV	+0.245	.001	6	view →
CHOL	All	II,III,IV	+0.875	<.001	5	view →
STAD	All	II,III,IV	+0.674	<.001	5	view →
HNSC	All	IV	+0.272	.002	5	view →
LUSC	All	All	+0.273	.001	3	view →
KIRP	Male	All	−0.249	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

CRTC3-AS1–KICH

Open the KICH breakdown →