CRTAP

Across TCGA patient cohorts, CRTAP protein abundance is significantly associated with the RNA expression of many other genes, with 19,158 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRTAP-associated genes across cancer lineages are SERPINE1, COL1A1, and DSE. Each is linked with CRTAP in more than 9 cancer types. Because this analysis shows association rather than direction, both CRTAP-to-partner and partner-to-CRTAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRTAP versus SERPINE1 in COAD, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRTAP→partner) and Y-score (partner→CRTAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SERPINE1 →	+1.799	+0.562	<.001	<.001	3	10
GBM	COL1A1 →	+2.658	+0.643	<.001	<.001	3	10
OV	DSE →	+0.968	+0.760	<.001	<.001	3	10
OV	FN1 →	+2.379	+0.599	<.001	<.001	3	10
UCEC	PXDN →	+1.124	+0.317	<.001	<.001	3	10
OV	COL5A1 →	+2.247	+0.708	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,158 associations by consensus.

CRTAP vs SERPINE1 — COAD

Explore this scatter interactively →