CRTAM

Across TCGA cell cohorts, CRTAM RNA expression is significantly associated with the go_rna of many other GO terms, with 626 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CRTAM-associated GO terms across cancer lineages are Viral process, Regulation of calcium ion transport into cytosol, and Regulation of homotypic cell-cell adhesion. Each is linked with CRTAM in more than 6 cancer types. Because this analysis shows association rather than direction, both CRTAM-to-partner and partner-to-CRTAM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral process grouped by CRTAM-low versus CRTAM-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CRTAM→partner) and Y-score (partner→CRTAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Viral process →	+0.078	+0.052	<.001	.005	3	7
LARGE_INTESTINE	Regulation of calcium ion transport into cytosol →	+0.181	+0.040	<.001	.001	1	7
SKIN	Regulation of homotypic cell-cell adhesion →	+0.052	+0.093	.003	.004	3	5
BLOOD_Leukemia	T cell activation →	+0.037	+0.323	.001	.007	3	5
LARGE_INTESTINE	Biological process involved in symbiotic interaction →	+0.075	+0.042	<.001	.001	2	5
BREAST	Biological process involved in interaction with host →	+0.080	+0.052	<.001	.004	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 626 associations by consensus.

Viral process by CRTAM expression — BREAST

Explore this box plot interactively →