CRTAM

Across TCGA pan-cancer cohorts, CRTAM RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated CRTAM data layer compared with 5 for mutation status.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher CRTAM RNA is associated with better overall survival. In most high-consensus cancer types, elevated CRTAM expression acts as an unfavorable survival marker, although some lineages such as SKCM and HNSC show a favorable association.

SKCM, HNSC, and UVM are the cancer types where CRTAM RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.431	0.256	<.001	131	view →
HNSC	DFS	Tertile	All	0.765	0.636	<.001	104	view →
UVM	DFS	Median	All	0.369	0.755	<.001	92	view →
CESC	DFS	Tertile	II,III,IV	0.907	0.648	.001	62	view →
LGG	OS	Median	All	0.753	0.862	<.001	43	view →
LUAD	DFS	Tertile	All	0.741	0.596	.001	42	view →
COAD	OS	Quartile	III,IV	0.674	0.350	.005	40	view →
LAML	DFS	Quartile	All	0.370	0.651	.003	36	view →
ACC	DFS	Tertile	All	0.776	0.334	.006	25	view →
KIRP	DFS	Quartile	All	0.426	0.944	<.001	25	view →
BRCA	DFS	Median	III,IV	0.916	0.832	.004	23	view →
LIHC	DFS	Median	III,IV	0.591	0.207	<.001	21	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

CRTAM–SKCM (OS)

Open the SKCM breakdown →