CRTAM

Across TCGA cell cohorts, CRTAM mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CRTAM-associated genes across cancer lineages are CLRN2, OR2T29, and MCHR2. Each is linked with CRTAM in more than 1 cancer types. Because this analysis shows association rather than direction, both CRTAM-to-partner and partner-to-CRTAM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLRN2 grouped by CRTAM-low versus CRTAM-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRTAM→partner) and Y-score (partner→CRTAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CLRN2 →	+0.036	+5.369	<.001	.004	3	1
SKIN	OR2T29 →	+0.012	+4.415	<.001	.007	3	1
LARGE_INTESTINE	MCHR2 →	+0.033	+4.684	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CLRN2 by CRTAM expression — SOFT_TISSUE

Explore this box plot interactively →